Romantic relationship break up: An experimental design to review negative effects of stress on despair (-like) episodes

The occurrence of a stressful event is considered to increase the risk of developing depression. In the present study we explore whether the breakup of a romantic relationship can be used as an experimental model to study a depression-like state during a period of stress in individuals without a psychiatric disorder. The primary aim of our study was to investigate: 1) whether individuals with a recent romantic relationship breakup (‘‘heartbreak”) demonstrate symptoms of depression, 2) how to describe heartbreak characteristics based on data from a comprehensive questionnaire battery, and 3) whether this description can capture severity of depression symptoms. Secondary, we were interested in gender differences with regard to the above study objectives. Subjects who have experienced a relationship breakup in the preceding six months (N = 71) or are in a romantic relationship (N = 46) participated in our study. A questionnaire battery was administered to acquire information related to depression, mood, the breakup and (former) relationship. Principal Component Analysis with Procrustes bootstrapping was performed to extract components from the questionnaire data. Even though our sample of individuals who recently have experienced a relationship breakup can be on average considered non-depressed, group-level depression scores were elevated compared to individuals in a relationship (p = .001) and 26.8% reported symptoms corresponding to mild, moderate or severe depression. We described heartbreak by two principal components interpreted as ‘‘sudden loss” and ‘‘lack of positive affect”, respectively. Highly significant correlations between the component scores and depression scores were found (p < .001 and p < .001, respectively), although these correlations differed between the genders. Based on these findings, we propose that the experience of a romantic relationship breakup is a viable experimental model to examine symptoms of depression in individuals without a psychiatric disorder. This way, stress-related coping and depression vulnerability can be studied in further research.

Citation: Verhallen In the morning, Renken RJ, ) Partnership breakup: A fresh design to study effects of strain bgclive beoordeling on depression (-like) symptoms. PLoS You to definitely 14(5): e0217320.

Copyright: © 2019 Verhallen et al. This really is an unbarred access blog post distributed in terms of the new Imaginative Commons Attribution License, hence it permits open-ended explore, shipments, and you may reproduction in almost any medium, given the first writer and you will supply are paid.

Connection break up: An experimental design to analyze ramifications of strain on anxiety (-like) symptoms

Research Accessibility: The info won’t be held on a public databases owed so you can limits on told agree (sufferers haven’t provided consent to has actually their investigation in public places held) and you can European studies privacy guidelines (GDPR). The content arrive to the demand. A document availability panel could have been put in place, including Prof Grams.J. ter Horst (Dominating Investigator of the research), J.B.C. Marsman and you can Prof A beneficial. Aleman (lead of your own Intellectual Neuroscience Cardiovascular system), who will opinion demands and you will to make certain usage of of the analysis. That it availability panel are going to be achieved thru

Funding: The analysis is financed because of the a donation of Mr Hazewinkel to help you the study College or university of Behavioural and you may Intellectual Neurosciences and you may Prof Grams.J. ter Horst. Mr Hazewinkel had no role within the studies structure, studies range and study, choice to share, or preparing of your manuscript.


Stressful life-events are thought to get risk activities toward development of despair. Kendler et al. investigated the interplay anywhere between stressful situations, hereditary predisposition and you may anxiety certainly female twins and discovered that both heredity and density away from stressful occurrences led to the fresh onset of depressive episodes separately. Particularly events with high perception, like loss of an almost partner and you may divorce or separation, increased the chances of developing a beneficial depressive event, as the majority of people do not build an excellent depressive episode following the contact with a distressing event. And that, research focusing on tiring and you will mentally hurtful events gives valuable skills with the private variations out of fret-related coping and also the results of stress and you will despair.